Grape Seed Extract

Grapes -- along with their leaves and sap -- have been traditional treatments in Europe for thousands of years. Grape seed extract is derived from the ground-up seeds of red wine grapes. Although fairly new to the U.S., grape seed extract is now used to treat a number of diseases.

Why do people take grape seed extract?

There’s strong evidence that grape seed extract is beneficial for a number of cardiovascular conditions. Grape seed extract may help with a type of poor circulation (chronic venous insufficiency) and high cholesterol. Grape seed extract also reduces swelling caused by injury and helps with eye disease related to diabetes.

Many people are interested in grape seed extract because it contains antioxidants. These are substances that protect cells from damage and may help prevent many diseases. However, it’s still too early to say whether the antioxidant properties of grape seed extract really benefit people. Researchers are studying grape seed extract to see if it might lower the risks of some cancers. For now, the evidence is not clear.

Grape seed extract has been studied for use in many other conditions -- ranging from PMS to skin damage to wound healing -- but the results have been inconclusive.

Shaklee's Vita-E Complex contain the natural vitamin E & selenium with grape seed extract. 

How much grape seed extract should you take?

There is no firmly established dose of grape seed extract. Doses of between 100-300 milligrams/day have been used in studies and are prescribed in some European countries. No one knows what the highest safe dose is.

Can you get grape seed extract naturally from foods?

Grape seed extract comes from grapes. There are no other food sources.

What are the risks of taking grape seed extract?

• Side effects. Grape seed extract is generally considered safe. Side effects may include headache, itchy scalp, dizziness, and nausea.
• Risks. People allergic to grapes should not use grape seed extract. If you have a bleeding disorder or high blood pressure, talk to your doctor before you start using grape seed extract.
• Interactions. If you take any medicines regularly, talk to your doctor before you start using grape seed extract. It could interact with drugs like blood thinners, NSAID painkillers (like aspirin, Advil, and Aleve), certain heart medicines, cancer treatments, and others.

Given the lack of evidence about its safety, grape seed extract is not recommended for children or for women who are pregnant or breastfeeding.

Source:www.webmd.com/vitamins-and-supplements/lifestyle-guide-11/grape-seed-extract

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Vitamin C

Vitamin C (L-ascorbic acid) essential nutrient for humans and certain other animal species. Vitamin C refers to a number of vitamers that have vitamin C activity in animals, including ascorbic acid and its salts, and some oxidized forms of the molecule like dehydroascorbic acid. Ascorbate and ascorbic acid are both naturally present in the body when either of these is introduced into cells, since the forms interconvert according to pH.

Vitamin C is a cofactor in at least eight enzymatic reactions, including several collagen synthesis reactions that, when dysfunctional, cause the most severe symptoms of scurvy. In animals, these reactions are especially important in wound-healing and in preventing bleeding from capillaries. Ascorbate may also act as an antioxidant against oxidative stress.

However, the fact that the enantiomer D-ascorbate (not found in nature) has identical antioxidant activity to L-ascorbate, yet far less vitamin activity, underscores the fact that most of the function of L-ascorbate as a vitamin relies not on its antioxidant properties, but upon enzymic reactions that are stereospecific. "Ascorbate" without the letter for the enantiomeric form is always presumed to be the chemical L-ascorbate.

Ascorbate (the anion of ascorbic acid) is required for a range of essential metabolic reactions in all animals and plants. It is made internally by almost all organisms; the main exceptions are most bats, all guinea pigs, capybaras, and the Anthropoidea and humans and other apes). All species that do not synthesize ascorbate require it in the diet. Deficiency in this vitamin causes the disease scurvy in humans.

Ascorbic acid is also widely used as a food additive, to prevent oxidation.

Scurvy
-leads to the formation of brown spots on the skin
-spongy gums
-bleeding from all mucous membranes.
The spots are most abundant on the thighs and legs, and a person with the ailment looks pale, feels depressed, and is partially immobilized. 

In advanced scurvy
-open, suppurating wounds and loss of teeth and, eventually, death.

The human body can store only a certain amount of vitamin C and so the body stores are depleted if fresh supplies are not consumed. The time frame for onset of symptoms of scurvy in unstressed adults on a completely vitamin C free diet, however, may range from one month to more than six months, depending on previous loading of vitamin C.

More reading, feel free to ask the Wikipedia ^_^
Credit to Wikipedia.

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